At USC, Innovation Isn’t Just a Word – It’s Our DNA.

USC Trojan entrepreneurs are fueling the future, one breakthrough at a time.

Who We Are

USC’s Innovation Ecosystem connects and empowers Trojan entrepreneurs, transforming groundbreaking research into real-world solutions.

Facilitated by the Office of Research and Innovation, we provide comprehensive support at every stage of the entrepreneurial journey, driving impact and advancing society.

By The Numbers

#11

USC’s rank in Inc. Magazine’s and Fast Company’s Ignition Schools list of Top 50 academic institutions for entrepreneurship and innovation

#4

Los Angeles’s rank in the 2024 Global Startup Ecosystem Report of the world’s leading startup ecosystems

#15

USC’s ranking of PitchBook’s Universities Top 100 global colleges ranked by startup founders

What We Do

Empowering Innovation at Every Stage

Inspire

Spark your entrepreneurial journey—USC’s early-stage programs ignite ideas, fuel innovation, and turn ambition into action!

Ignite

From spark to startup—Office of Research and Innovation’s seed funding and internal support programs help early-stage ventures gain traction and thrive.

Invest

Big ideas deserve bold backing—USC strategically invests in its entrepreneurs to accelerate startup success.

Innovation Allies: Our Team

USC’s innovation ecosystem is powered by internal and external partners dedicated to Trojan entrepreneurs. Meet the allies who help turn groundbreaking ideas into real-world impact.

Innovation Core

Office of Research Initiatives and Infrastructure

Learn more at rii.usc.edu

Office of Research Strategy and Development

Learn more at rsd.usc.edu

USC Stevens Center for Innovation

Learn more at stevens.usc.edu

USC Alfred E. Mann Institute

Email us at twarsi@usc.edu

Foundational Partner

Digital Economy Program

USC + Techstars Partnership

Campus Partners

Innovation Quest

USC Marshall School of Business

Lloyd Greif Center for Entrepreneurial Studies

USC Viterbi School of Engineering

Technology Innovation & Entrepreneurship

USC Viterbi School of Engineering

I-Corps Hub:
West Region

Keck School of Medicine of USC

MESH Strategic Partnerships

News & Events: The Pulse of Innovation

Latest News

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  • USC AMI Makes Exciting Investment in USC Faculty-Led Company, CpG Diagnostics
    by Jordan Locy on October 27, 2025 at 5:12 pm

    Author: Jordan Locy, Ethan Bochicchio & Aaron K. Nordman In September 2020, Dr. Bodour Salhia founded CpG Diagnostics, intent on transforming cancer diagnostics through innovative epigenetic technology. High-grade serous ovarian cancer (HGSOC), the most aggressive subtype of epithelial ovarian cancer, requires timely specialist management. Utilizing the patented OvaPrint, the only cell-free DNA methylation blood test…

  • USC AMI Makes Exciting Investment in USC Faculty-Led Company, Plurocart
    by Jordan Locy on October 6, 2025 at 6:20 pm

    Author: Jordan Locy & Ethan Bochicchio In late 2021, researchers Denis Evseenko and Frank Petrigliano were awarded a $6 million grant from the California Institute of Regenerative Medicine for their breakthrough, having used a stem cell-based bio-implant to delay joint degeneration and repair cartilage in a large animal model. Today, joined by Jay R. Lieberman,…

  • USC and Techstars Welcome New Cohort of University Catalyst Companies
    by Jordan Locy on September 12, 2025 at 5:54 pm

    The University of Southern California (USC) and Techstars are proud to announce the newest cohort of university catalyst companies selected for the USC and Techstars program. The USC and Techstars program is a collaborative effort led by USC’s Office of Research and Innovation (OORI), that brings Techstars expertise and programmatic offerings to USC students and…

  • USC OORI News: Applications Now Open for the 2026 USC & Techstars Accelerator
    by Jordan Locy on September 12, 2025 at 5:19 pm

    The University of Southern California (USC) and Techstars are thrilled to announce that applications for the 2026 USC & Techstars Accelerator are officially open as of August 25, 2025. The USC and Techstars program is a collaborative effort led by USC’s Office of Research and Innovation (OORI) that brings Techstars’ expertise and programmatic offerings to…

  • USC’s Alfred E. Mann Institute Set to Announce New Innovation-Driven Investments
    by Jordan Locy on September 8, 2025 at 11:47 pm

    The University of Southern California’s Alfred E. Mann Institute (AMI) is preparing to announce a new round of strategic investments in groundbreaking medical technologies and innovations. Under the leadership of Managing Director Tariq Warsi, AMI continues to advance its mission of bridging the gap between early-stage biomedical research and commercially viable products that improve and…

Upcoming Events

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Success Stories: Trojan Entrepreneurs in Motion