At USC, Innovation Isn’t Just a Word – It’s Our DNA.
USC Trojan entrepreneurs are fueling the future, one breakthrough at a time.
Who We Are
USC’s Innovation Ecosystem connects and empowers Trojan entrepreneurs–transforming groundbreaking research into
startups, technologies, and real-world solutions.
Facilitated by the Office of Research and Innovation, we support innovators at every stage of the entrepreneurial journey, from discovery and company formation to venture growth and global impact.
By The Numbers
$1B+
Annual research expenditures
$32B+
Venture capital raised by USC alumni-founded startups (PitchBook)
#7
Los Angeles’s ranking in the Global Startup Ecosystem Report of the world’s leading startup ecosystems
#17
USC’s ranking in Fast Company and Inc.’s Ignition Schools list of the world’s top universities for entrepreneurship and innovation
Inspire
Spark your entrepreneurial journey—USC’s early-stage programs ignite ideas, fuel innovation, and turn ambition into action!
Ignite
From spark to startup—Office of Research and Innovation’s seed funding and internal venture support programs help early-stage ideas gain traction and thrive.
Invest
Big ideas deserve bold backing—USC strategically invests in its entrepreneurs to accelerate startup growth and real-world impact.
Innovation Leadership
Strategic Partner

Learn more at techstars.com/usc-and-techstars-programs
Campus Innovation Partners

Innovation Quest

Lloyd Greif Center for Entrepreneurial Studies

Technology Innovation & Entrepreneurship

I-Corps Hub: West Region

MESH Strategic Partnerships
Innovation News & Events
Latest News
- OORI Highlights Innovation Resources at USC Space Engineering Research Center Industry Open Houseby Jordan Locy on July 30, 2026 at 12:40 am
OORI showcases the resources, partnerships, and commercialization support helping USC researchers advance the next generation of space technologies. Author – Ethan Bochicchio The University of Southern California’s Office of Research and Innovation (OORI) participated in the inaugural USC Space Engineering Research Center (SERC) Industry Open House at the USC Information Sciences Institute on July 15,…
- Behind the Pitch: OORI Helps USC Techstars Founders Prepare for Growthby Jordan Locy on July 29, 2026 at 3:36 am
The Office of Research and Innovation helps select, support, and connect the eight companies participating in the 2026 USC Techstars Accelerator. Author – Ethan Bochicchio Eight startup founders took the stage at the 2026 USC Techstars Demo Day, presenting the companies they had spent months building and refining before an audience of investors, industry leaders,…
- Office of Research & Innovationby Jordan Locy on June 30, 2026 at 5:49 pm
MONTHLY NEWSLETTER – JUNE 2026 Dear USC Research & Innovation Partners, I want to recognize your extraordinary work during this fiscal year and share updates on three developments affecting USC’s research enterprise. Research Funding Momentum Continues: Despite an increasingly competitive and uncertain federal funding environment, USC’s research enterprise continues to demonstrate exceptional strength and…
- Office of Research & Innovationby Jordan Locy on May 31, 2026 at 5:41 pm
MONTHLY NEWSLETTER – MAY 2026 Dear Colleagues, As we move into the summer, I thank you — our extraordinary research and innovation community. Your creativity, dedication, and drive continue to move USC’s mission forward in meaningful ways, and I am deeply grateful for all that you do. While the rhythm of campus may shift during…
- From Idea to Pitch: OORI and Techstars Bring USC Founders Together for Startup Weekendby Jordan Locy on May 22, 2026 at 5:29 pm
Author – Ethan Bochicchio Over the course of 54 hours, Trojan entrepreneurs moved from early ideas to final pitches during the 2026 USC and Techstars Startup Weekend, a three-day innovation experience coordinated by the Office of Research and Innovation (OORI) in partnership with Techstars. Throughout the weekend, USC students, faculty, staff, and alumni came together to pitch…
Upcoming Events
Trojan Innovators in Action

Turning Ideas into Startups Through the OORI Innovation Empowerment Award
“The mentorship and funding gave me the freedom to experiment, validate ideas, and make real progress in the early stages of building my startup.”
Jessie Tran, Student
Master of Science, Entrepreneurship and Innovation
USC Marshall School of Business

Advancing Biomedical Innovation Through USC Research and Commercialization
“OORI’s support—from grant development to commercialization—has been instrumental in advancing innovation across my research programs.”
Mark Humayun, Faculty
University Professor of Ophthalmology and Biomedical Engineering
Cornelius J. Pings Chair in Biomedical Sciences, Director, USC Ginsburg Institute for Biomedical Therapeutics
Co-Director, USC Roski Eye Institute
Keck School of Medicine of USC

Building AI Tools to Make Healthcare More Accessible
“The OORI Student Empowerment Award helped us accelerate development of AI tools that make healthcare more
affordable and accessible.”
Dhruv Deshmukh, Student
Bachelor of Science, Computer Science
USC Viterbi School of Engineering

Gaining Real Startup Experience Through USC Techstars Partnership
“Working with USC Techstars gave me the real-world experience, mentorship, and confidence to take the first steps toward launching my own venture.”
Wednesday Satterlee, Student
BS, Business Administration
Marshall School of Business

Advancing a Student Healthtech Startup with the Empowerment Award
“The Student Empowerment Award is helping us advance our healthtech startup to the next stage by supporting technical development and early growth.”
Miki Safronov, Student
BS, Human-Centered Design, Technology, Entrepreneur, and Communication
Iovine and Young Academy

Accelerating Startup Growth Through USC Techstars Partnership
“USC Techstars gave our startup the funding, mentorship, and network we needed to test ideas, find product-market fit, and accelerate growth.”
Rex Ordonez, Student
Bachelors, Computer Science & Business
USC Viterbi School of Engineering

Scaling a Student Startup with the OORI Student Empowerment Award
“The OORI Student Empowerment Award helped accelerate Treffa’s growth and gave me the support to build a venture that can create real impact beyond USC.”
Anantika Mannby, Student
BS, Arts, Technology and the Business of Innovation
Iovine and Young Academy

Advancing Research Translation Through OORI Support
“OORI’s programs and support have been invaluable in helping translate my research into real-world innovation and connecting our work to industry.”
David Barnhart, Faculty
Research Professor of Astronautics
Department of Astronautical Engineering
Viterbi Information Sciences Institute


