At USC, Innovation Isn’t Just a Word – It’s Our DNA.

USC Trojan entrepreneurs are fueling the future, one breakthrough at a time.

Who We Are

USC’s Innovation Ecosystem connects and empowers Trojan entrepreneurs, transforming groundbreaking research into real-world solutions.

Facilitated by the Office of Research and Innovation, we provide comprehensive support at every stage of the entrepreneurial journey, driving impact and advancing society.

By The Numbers

#11

USC’s rank in Inc. Magazine’s and Fast Company’s Ignition Schools list of Top 50 academic institutions for entrepreneurship and innovation

#4

Los Angeles’s rank in the 2024 Global Startup Ecosystem Report of the world’s leading startup ecosystems

#15

USC’s ranking of PitchBook’s Universities Top 100 global colleges ranked by startup founders

What We Do

Empowering Innovation at Every Stage

Inspire

Spark your entrepreneurial journey—USC’s early-stage programs ignite ideas, fuel innovation, and turn ambition into action!

Ignite

From spark to startup—Office of Research and Innovation’s seed funding and internal support programs help early-stage ventures gain traction and thrive.

Invest

Big ideas deserve bold backing—USC strategically invests in its entrepreneurs to accelerate startup success.

Innovation Allies: Our Team

USC’s innovation ecosystem is powered by internal and external partners dedicated to Trojan entrepreneurs. Meet the allies who help turn groundbreaking ideas into real-world impact.

Innovation Core

Office of Research Initiatives and Infrastructure

Learn more at rii.usc.edu

Office of Research Strategy and Development

Learn more at rsd.usc.edu

USC Stevens Center for Innovation

Learn more at stevens.usc.edu

USC Alfred E. Mann Institute

Email us at twarsi@usc.edu

Foundational Partner

Digital Economy Program

USC + Techstars Partnership

Campus Partners

Innovation Quest

USC Marshall School of Business

Lloyd Greif Center for Entrepreneurial Studies

USC Viterbi School of Engineering

Technology Innovation & Entrepreneurship

USC Viterbi School of Engineering

I-Corps Hub:
West Region

Keck School of Medicine of USC

MESH Strategic Partnerships

News & Events: The Pulse of Innovation

Latest News

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  • OORI Unlocks Microsoft for Startups Resources for USC Entrepreneurs
    by Jordan Locy on March 27, 2026 at 9:42 pm

    Author – Ethan Bochicchio Through its expanding network of external collaborators, the Office of Research and Innovation (OORI) has enabled USC founders to access Microsoft for Startups resources by joining the Microsoft for Startups Investor Network. This engagement offers benefits to Trojan entrepreneurs, including cloud credits, go-to-market support, and AI tools. By building these partnerships,…

  • AMI Makes Exciting Investment in Innata Bio
    by Jordan Locy on March 26, 2026 at 7:42 pm

    By – Ethan Bochicchio & Jordan Locy Innata Bio is an inflammation-modulation platform company at the clinical stage, focused on developing advanced treatments to address aging-related inflammation. Co-founded by USCS’s Dr. Denis Evseenko, Innata Bio has identified a key link between inflammation and cellular aging and has created a patented platform to reverse this process.…

  • USC/OORI Funded App Corresi Shows Promising Success
    by Jordan Locy on March 26, 2026 at 4:22 pm

    Author – Ethan Bochicchio At the University of Southern California (USC), the Office of Research and Innovation (OORI) is turning early-stage ideas into real-world impact, as demonstrated by the success of Corresi. Starting in 2024 through the OORI-funded Innovation Empowerment Initiative, a part of OORI’s Innovation Catalyst Program, Corresi quickly developed into a launched app…

  • USC OORI Helps 12 Innovators Earn National Academy of Inventors Senior Membership
    by Jordan Locy on March 3, 2026 at 5:20 pm

    Author – Ethan Bochicchio The Office of Research and Innovation (OORI) successfully assisted 12 University of Southern California faculty members in being selected as Senior Members of the National Academy of Inventors (NAI), the prestigious nonprofit organization dedicated to encouraging inventors in academia. This recognition celebrates academic inventors whose patented work has made measurable contributions to society…

  • USC and Techstars Celebrate a Powerful University Catalyst Cohort Graduation
    by Jordan Locy on January 23, 2026 at 5:37 pm

    Author – Ethan Bochicchio Another successful USC and Techstars University Catalyst Program has come to a close, marking a significant milestone in the evolution of USC’s innovation and entrepreneurship ecosystem. Over ten weeks, the program transformed early-stage ideas into more disciplined, market-ready ventures, while giving founders a clearer understanding of what it takes to build…

Upcoming Events

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Success Stories: Trojan Entrepreneurs in Motion